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IN VITRO EVALUATION OF EXPERIMENTAL FLUORIDE TAPE IN INHIBITION OF ENAMEL DEMINERALIZATION

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Abstract

º» ¿¬±¸ÀÇ ¸ñÀûÀº ¹ý¶ûÁú Ç¥¸é ¹Ì¼¼°æµµÀÇ ÃøÁ¤°ú ÁÖ»çÀüÀÚÇö¹Ì°æ °üÂûÀ» ÅëÇØ º» ±³½Ç¿¡¼­ °³¹ßÇÑ 2.26%ÀÇ ºÒ¼Ò¸¦ ÇÔÀ¯ÇÑ Æú¸®ºñ´Ò¾ËÄÚ¿Ã Å×ÀÙ (F-PVA tape)ÀÇ ¹ý¶ûÁú Żȸ ¾ïÁ¦ È¿°ú¸¦ Æò°¡Çϱâ À§ÇÑ °ÍÀÌ´Ù. 60°³ÀÇ ¹ý¶ûÁú Ç¥º»À» °¢ ±º´ç 15°³ ¾¿, ÀÓÀÇ·Î ´ëÁ¶±º, F-PVA tape ±º, ºÒ¼Ò¹Ù´Ï½¬ ±º, CPP-ACFP ±ºÀ¸·Î ³ª´©°í, °¢°¢ÀÇ À籤ȭ Á¦À縦 µµÆ÷ÇÑ ÈÄ pH-cycling °úÁ¤ °ÅÃÆ´Ù. Ç¥º»ÀÇ Ç¥¸é ¹Ì¼¼°æµµ¸¦ ÃøÁ¤ÇÏ°í Ç¥¸é ¹Ì¼¼°æµµ ¼Ò½Ç·®À» °è»êÇÏ¿´´Ù. ÁÖ»çÀüÀÚÇö¹Ì°æ °üÂûÀ» À§ÇØ, °¢ ±º¿¡¼­ 5°³ÀÇ Ç¥º»À» ÃßÃâÇÏ°í ÇüÅÂÇÐÀû Ư¡À» ºÐ¼®ÇÏ¿´°í ´ÙÀ½°ú °°Àº °á·ÐÀ» ¾ò¾ú´Ù. 1. pH-cycling ÈÄ, F-PVA tape ±º°ú ºÒ¼Ò¹Ù´Ï½¬ ±ºÀÇ ¹ý¶ûÁú Ç¥¸é ¹Ì¼¼°æµµ °ªÀº CPP-ACFP ±º°ú ºñ±³ ½Ã À¯ÀÇÇÏ°Ô ³ô¾ÒÀ¸¸ç, F-PVA tape ±º°ú ºÒ¼Ò¹Ù´Ï½¬ ±º »çÀÌ¿¡´Â À¯ÀÇÇÑ Â÷ÀÌ°¡ ¾ø¾ú´Ù. 2. ÁÖ»çÀüÀÚÇö¹Ì°æ °üÂû ½Ã, F-PVA tape ±º°ú ºÒ¼Ò¹Ù´Ï½¬ ±º¿¡¼­´Â ¹ý¶ûÁú Ç¥¸é¿¡ Çü¼ºµÈ ¼ö¸¹Àº ±¸Çü ¹× ³­¿øÇüÀÇ °áÁ¤ ÀÔÀÚµéÀÌ °üÂûµÇ¾úÀ¸¸ç, °áÁ¤ ÀÔÀÚÀÇ ¹Ðµµ´Â ´ëÁ¶±º ¹× CPP-ACFP ±º¿¡¼­ º¸´Ù ³ô¾Ò´Ù. F-PVA tapeÀº ¹ý¶ûÁúÀÇ Å»È¸¸¦ ¾ïÁ¦Çϴµ¥ È¿°úÀûÀ̸ç, ±× È¿°ú´Â ºÒ¼Ò¹Ù´Ï½¬¿Í °ßÁÙ¸¸ÇÏ°í, CPP-ACFP º¸´Ù ¿ì¼öÇÏ´Ù.

The aim of this in vitro study was to evaluate the effectiveness of experimental 2.26% fluoride-polyvinyl alcohol (F-PVA) tape in inhibition of enamel demineralization using enamel surface microhardness (SMH) analysis and scanning electron microscopy (SEM) examination. Enamel specimens (n=60) randomly assigned to four groups: control group, F-PVA tape group, fluoride varinish (F-varnish) group, casein phosphopeptide-amorphous calcium phosphate (CPP-ACFP) group. After topical application, pH-cycling was processed. Then, SMH was measured and the percentage loss of surface microhardness (%SML) was calculated. For the SEM examination, five sample specimens in each group were treated and the morphologic character was evaluated. After pH-cycling, the SMH values of the enamel specimens of F-PVA tape and F-varnish group were significantly higher than that of CPP-ACFP group, there was no significant difference between F-PVA tape and Fvarnish group. With SEM examination, enamel surfaces in the F-PVA tape group and F-varnish group showed numerous spherical and ovoid crystals formed on the enamel surface were also observed. The density of crystals was higher than that of both control group and CPP-ACFP group. F-PVA tape is effective in inhibition of enamel demineralization. Also, F-PVA tape¡¯s inhibition of enamel demineralization is comparable to that of F-vanish and greater than that of CPP-ACFP.

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ºÒ¼Ò Å×ÀÌÇÁ; ¹ý¶ûÁú Żȸ
Fluoride tape; PVA tape; Enamel demineralization

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